Question: What neutral nucleophile is needed to convert C to D? Imatinib, an effective treatment for certain cancers, is prepared in one step from D.
The neutral nucleophile that is needed to convert C to D is given below:
Nucleophiles that do not possess a charge are referred to as neutral nucleophiles. Some examples of neutral nucleophiles include , R-OH and R-O-R.
Imatinib belongs to the category of medication “kinase inhibitor.”
It can cure certain kinds of cancer and other conditions like gastrointestinal stromal tumors and acute lymphocytic leukemia.
The neutral nucleophile that is required to transform C to D is:
The chlorine atom of compound C is replaced by a nitrogen atom through a new group. This indicates that a substitution reaction is also taking place within the reaction. The lone pair of electrons on the nitrogen atom strikes the electron-deficient atom to form product D as:
Question: Consider the following SN2 reaction.
94% of StudySmarter users get better grades.Sign up for free