Question: Pick the reactant or solvent in each part that gives the faster SN2 reaction.
The mechanism of the SN2 reactions depends upon the following factors:
This is because the presence of a strong nucleophile will result in the formation of the transition state quickly. The rate of the reaction also depends upon the concentration of the nucleophile.
a. The reaction of OH- with CH3CH2Br is faster as compared to the reaction between OH- and CH3CH2Cl .
This Br- is because the is a better leaving group as compared to the Cl- ion.
b. The reaction of CH3CH2CH2Cl with NaOH is faster. The NaOH will produce OH- which is a stronger nucleophile as compared to OCOCH3.
c.The reaction of CH3CH2CH2I with -OCH3by using DMSO as a solvent will be faster.
DMSO refers to dimethyl sulfoxide has a chemical formula of (CH3)2SO . It is a polar aprotic solvent. The rate of SN2 the reaction increases by using the aprotic solvent.
On the other hand, methanol (CH3OH) is a polar protic solvent and is unfavorable for the reactions.
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